Anycubic Kobra X Combo vs Prusa Research MK4S kit
Technical comparison · Fused filament fabrication (FFF/FDM)
Two Cartesian filament printers with a bed of about 250 mm, for someone who wants a working machine without paying flagship money. Price decides it: the Kobra X Combo costs €230 less, and that buys a bigger bed, more height and multicolor without an add-on module.
| Parameter | ||
|---|---|---|
| Identity | ||
| Launch year | 2026 | 2025 |
| Use tier | F2 — Intermediate | F2 — Intermediate |
| Price | ||
| Price (€) | 589 € | 819 € |
| Price updated on | 06/2026 | — |
| Universal specs | ||
| Dimensions (W×D×H) (cm) | 45.54 × 44.53 × 46.13 cm | 50 × 55 × 40 cm |
| Weight (kg) | 13.2 kg | 7 kg |
| Work area (mm) | 260 × 260 mm | 250 × 210 mm |
| Z-axis height (mm) | 260 mm | 220 mm |
| Power (W) | — | 240 W |
| Voltage (V) | — | 230 V |
| Maximum speed | 600 mm/s | 500 mm/s |
| Category specs | ||
| Footprint X×Y (short side) (mm) | 260 mm | 250 mm |
| Build height Z (mm) | 260 mm | 220 mm |
| Kinematics | Cartesian | Cartesian |
| Max nozzle temperature (°C) | 300 °C | 290 °C |
| Max bed temperature (°C) | 100 °C | 120 °C |
| Max print speed (mm/s) | 600 mm/s | 500 mm/s |
| Enclosed chamber | No | No |
| Filament sensor | Yes | Yes |
| Auto bed leveling | Mesh | Mesh |
| Standard nozzle diameter (mm) | 0.4 mm | 0.4 mm |
| Multi-extruder | No | No |
| Native Klipper | Yes | No |
| Input shaper | Yes | Yes |
| Multicolor printing | Yes | Yes |
| Multicolor requires accessory | No | Yes |
| Max colors | 4 | 5 |
| Ecosystem | ||
| Cloud dependency | No | No |
| Software notes | Powered by Kobra OS (a Klipper fork), it features Wi-Fi connectivity, vibration compensation, dynamic flow calibration, and a camera with built-in AI detection. | The MK4S runs proprietary Prusa firmware based on Marlin, not GRBL. It is managed through PrusaSlicer (with over 180 official profiles included), Simplify3D, or Cura with community profiles. Files are loaded via USB, local network, or PrusaConnect and the Prusa mobile app; it is not compatible with LightBurn or LaserGRBL, being a filament printer. The machine can run fully offline with no cloud dependency, and receives regular firmware updates along with pre-tuned profiles for Prusament materials. |
The differences that matter
- €589 vs €819 → €230 left over for filament and accessories.
- Bed 260×260 mm and 260 mm tall vs 250×210 mm and 220 mm → a part 250 mm tall fits on the Kobra, not on the MK4S.
- Multicolor up to 4 colors with no accessory vs up to 5 with one → on the MK4S the extra color costs a module.
- Bed at 100 °C vs 120 °C → materials that call for a 120 °C bed sit better on the MK4S.
Which one to choose
Choose Kobra X Combo if…
On Monday morning you print a part 250 mm tall or a 260×260 mm tray in four colors without buying anything else; the MK4S stops at 220 mm in height. The firmware is Klipper, with the Anycubic app and camera. The trade-off: the bed heats to 100 °C against the MK4S's 120 °C, and you don't get the tuned Prusament profiles Prusa ships for its own filaments. Temperatures and speeds are manufacturer-declared values.
Choose MK4S kit if…
You print every day with PrusaSlicer, which ships with over 180 official profiles, and want a machine that also runs fully offline, from USB, local network or PrusaConnect. You accept paying €230 more for a 250×210 mm bed and, if you need multicolor, an accessory: with it you reach 5 colors, one more than the Kobra.
Where to buy
Paid link: the price for you does not change. Methodology
Filaments for these printers
The most chosen spools among the materials both printers can print according to their specifications.
- ELEGOO PLA PLA1.75 mm1 kg Check the price on Amazon →
- Bambu Lab PLA PLA1.75 mm1 kg Check the price on Amazon →
- SUNLU PETG (Polyethylene Terephthalate Glycol) PETG (Polyethylene Terephthalate Glycol)1.75 mm1 kg Check the price on Amazon →
- SUNLU PLA PLA1.75 mm1 kg Check the price on Amazon →
- OVERTURE PETG (Polyethylene Terephthalate Glycol) PETG (Polyethylene Terephthalate Glycol)High speed1.75 mm1 kg Check the price on Amazon →
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