Anycubic Kobra S1 Max Combo vs Prusa Research MK4S kit
Technical comparison · Fused filament fabrication (FFF/FDM)
The prices are close, but the two machines are built for different part sizes: the Kobra S1 Max Combo prints in an enclosed chamber over 350 × 350 × 350 mm, the MK4S over 250 × 210 × 220 mm with an open frame. Everything else matters less than that.
| Parameter | ||
|---|---|---|
| Identity | ||
| Launch year | 2025 | 2025 |
| Use tier | F2 — Intermediate | F2 — Intermediate |
| Price | ||
| Price (€) | ~799–1099 € | 819 € |
| Price updated on | 06/2026 | — |
| Universal specs | ||
| Dimensions (W×D×H) (cm) | 50.27 × 48.3 × 58.4 cm | 50 × 55 × 40 cm |
| Weight (kg) | — | 7 kg |
| Work area (mm) | 350 × 350 mm | 250 × 210 mm |
| Z-axis height (mm) | 350 mm | 220 mm |
| Power (W) | 2200 W | 240 W |
| Voltage (V) | 220 V | 230 V |
| Maximum speed | 600 mm/s | 500 mm/s |
| Declared precision | 0.05 mm | — |
| Category specs | ||
| Footprint X×Y (short side) (mm) | 350 mm | 250 mm |
| Build height Z (mm) | 350 mm | 220 mm |
| Kinematics | CoreXY | Cartesian |
| Max nozzle temperature (°C) | 350 °C | 290 °C |
| Max bed temperature (°C) | 120 °C | 120 °C |
| Max print speed (mm/s) | 600 mm/s | 500 mm/s |
| Enclosed chamber | Yes | No |
| Filament sensor | Yes | Yes |
| Auto bed leveling | Mesh | Mesh |
| Standard nozzle diameter (mm) | 0.4 mm | 0.4 mm |
| Multi-extruder | No | No |
| Native Klipper | No | No |
| Input shaper | Yes | Yes |
| Multicolor printing | Yes | Yes |
| Multicolor requires accessory | Yes | Yes |
| Max colors | 4 | 5 |
| Ecosystem | ||
| Cloud dependency | No | No |
| Software notes | The firmware runs on a proprietary Kobra OS layer built on top of Klipper; the official slicer is Anycubic Slicer Next, derived from OrcaSlicer, available for Windows and macOS. Third-party OrcaSlicer is also supported. Remote monitoring and control are available via the Anycubic app (iOS/Android) over LAN, with no mandatory cloud connection required for core printing functions. | The MK4S runs proprietary Prusa firmware based on Marlin, not GRBL. It is managed through PrusaSlicer (with over 180 official profiles included), Simplify3D, or Cura with community profiles. Files are loaded via USB, local network, or PrusaConnect and the Prusa mobile app; it is not compatible with LightBurn or LaserGRBL, being a filament printer. The machine can run fully offline with no cloud dependency, and receives regular firmware updates along with pre-tuned profiles for Prusament materials. |
The differences that matter
- Volume 350 × 350 × 350 mm against 250 × 210 × 220 mm → a 30 cm part fits whole on the Kobra; on the MK4S it has to be split.
- Nozzle up to 350 °C against 290 °C → the Kobra takes materials the MK4S cannot print.
- PrusaSlicer with over 180 official profiles → the MK4S starts from ready-made settings.
- Price about 949 € against 819 € → the MK4S costs about 130 euro less.
Which one to choose
Choose Kobra S1 Max Combo if…
you print large parts, such as a 30 cm housing or bracket, or materials that need a nozzle up to 350 °C in an enclosed chamber (manufacturer-declared values). You accept paying about 130 euro more than the MK4S.
Choose MK4S kit if…
you print parts within 250 × 210 × 220 mm and want to work with PrusaSlicer, which ships with over 180 official profiles and ready-made Prusament profiles, even offline. You give up the enclosed chamber and any nozzle temperature above 290 °C.
Where to buy
Paid link: the price for you does not change. Methodology
Filaments for these printers
The most chosen spools among the materials both printers can print according to their specifications.
- ELEGOO PLA PLA1.75 mm1 kg Check the price on Amazon →
- Bambu Lab PLA PLA1.75 mm1 kg Check the price on Amazon →
- SUNLU PETG (Polyethylene Terephthalate Glycol) PETG (Polyethylene Terephthalate Glycol)1.75 mm1 kg Check the price on Amazon →
- SUNLU PLA PLA1.75 mm1 kg Check the price on Amazon →
- OVERTURE PETG (Polyethylene Terephthalate Glycol) PETG (Polyethylene Terephthalate Glycol)High speed1.75 mm1 kg Check the price on Amazon →
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