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Anycubic Kobra 4 Combo vs Anycubic Kobra S1

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Choose Anycubic Kobra 4 Combo if you are looking for a lightweight entry-level system (13.6 kg) with integrated multi-color printing up to 4 colors, at a price of 499 €. Choose Anycubic Kobra S1 if you need to print materials requiring higher temperatures (320 °C at the nozzle) in an enclosed chamber, relying on intermediate-tier CoreXY kinematics at 549 €.

Parameter
Identity
Launch year 2026 2025
Use tier F1 — Entry F2 — Intermediate
Price
Price (€) 499 € 549 €
Price updated on 06/2026 06/2026
Universal specs
Dimensions (W×D×H) (cm) 45.54 × 44.53 × 46.13 cm 40 × 41 × 49 cm
Weight (kg) 13.6 kg 18 kg
Work area (mm) 260 × 260 mm 250 × 250 mm
Z-axis height (mm) 260 mm 250 mm
Maximum speed 600 mm/s 600 mm/s
Declared precision — 0.05 mm
Category specs
Footprint X×Y (short side) (mm) 260 mm 250 mm
Build height Z (mm) 260 mm 250 mm
Kinematics Cartesian CoreXY
Max nozzle temperature (°C) 300 °C 320 °C
Max bed temperature (°C) 100 °C 120 °C
Max print speed (mm/s) 600 mm/s 600 mm/s
Enclosed chamber No Yes
Filament sensor Yes Yes
Auto bed leveling Mesh Mesh
Standard nozzle diameter (mm) 0.4 mm 0.4 mm
Multi-extruder No No
Native Klipper Yes Yes
Input shaper Yes Yes
Multicolor printing Yes Yes
Multicolor requires accessory No Yes
Max colors 4 8
Ecosystem
Cloud dependency No No
Software notes Equipped with Kobra OS firmware. It supports connectivity via USB, Anycubic Slicer, and the Anycubic mobile app for remote print monitoring and control. Integrates AI-based error detection. The Kobra OS firmware is based on Klipper and controlled via a proprietary touch interface. The official slicer is Anycubic Slicer Next (derived from OrcaSlicer, available for Windows and macOS), but it also supports third-party OrcaSlicer. Remote control is possible via the Anycubic app (iOS/Android) over a local network, with no mandatory cloud connection for daily operations.

The differences that matter

  • Kinematics and Structure: Kobra S1 uses a CoreXY system with an enclosed chamber weighing 18 kg, while Kobra 4 Combo adopts an open Cartesian kinematic design weighing 13.6 kg.
  • Multi-color Management: Kobra 4 Combo natively manages up to 4 colors without external accessories, unlike Kobra S1 which supports up to 8 colors but requires an auxiliary device.
  • Maximum Temperatures: The nozzle and bed of Kobra S1 reach 320 °C and 120 °C respectively, higher than the 300 °C and 100 °C offered by the Kobra 4 Combo.
  • Build Volume: Kobra 4 Combo provides a marginally more spacious operational area (260 × 260 × 260 mm) against the 250 × 250 × 250 mm area of Kobra S1.
  • Tier and Price: Kobra 4 Combo is positioned as entry-level (F1) at 499 €, while Kobra S1 belongs to the intermediate tier (F2) priced at 549 €.

Which one to choose

Choose Kobra 4 Combo if…

Choose Anycubic Kobra 4 Combo for an entry-level (F1 tier) approach to fused filament 3D printing, prioritizing a slightly larger build volume (260 × 260 × 260 mm compared to 250 mm on the S1) and a lower entry cost (499 € vs 549 €). It is suitable if you want native multi-color printing up to 4 colors without requiring external accessories, accepting an open Cartesian structure design.

See the Kobra 4 Combo sheet →

Choose Kobra S1 if…

Choose Anycubic Kobra S1 for intermediate-level usage (F2 tier) that benefits from an enclosed CoreXY structure, ideal for handling higher temperatures (up to 320 °C at the nozzle and 120 °C at the heated bed). It is the optimal choice if you plan to expand multi-color printing up to 8 colors via an external accessory and need a machine with greater mass and structural stability (18 kg).

See the Kobra S1 sheet →

Where to buy

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Filaments for these printers

The most chosen spools among the materials both printers can print according to their specifications.

All filaments →

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MakerSpecs is an independent atlas. We don't sell products: the purchase links are the same as on the two product sheets and don't influence the verdict. The sheets have the complete data.