Neptune 4 Pro vs Original Prusa MK4S 3D Printer kit

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Neptune 4 Pro and Original Prusa MK4S 3D Printer kit are two fused filament fabrication (fff/fdm) in a similar class. Choose Neptune 4 Pro if price matters more; choose Original Prusa MK4S 3D Printer kit if maximum colors matters more.

Parameter
Elegoo Neptune 4 Pro Neptune 4 Pro Elegoo F2 · Intermediate
Identity
Launch year 2023 2025
Use tier F2 — Intermediate F2 — Intermediate
Price
Price (€) 299 € 819 €
Universal specs
Dimensions (W×D×H) (cm) 47.5 × 44.5 × 51.5 cm 50 × 55 × 40 cm
Weight (kg) 8.9 kg 7 kg
Work area (mm) 225 × 225 mm 250 × 210 mm
Z-axis height (mm) 265 mm 220 mm
Power (W) 240 W
Voltage (V) 230 V
Maximum speed 500 mm/s 500 mm/s
Declared precision 0.1 mm
Category specs
XY print surface (mm) 225 mm 250 mm
Maximum Z height (mm) 265 mm 220 mm
Kinematics cartesian cartesian
Max nozzle temperature (°C) 300 °C 290 °C
Max bed temperature (°C) 110 °C 120 °C
Max print speed (mm/s) 500 mm/s 500 mm/s
Closed chamber False False
Filament sensor True True
Auto leveling mesh mesh
Standard nozzle diameter (mm) 0.4 mm 0.4 mm
Multi-extruder False False
Native Klipper True False
Input shaper True True
Multicolor printing False True
Requires external accessory False True
Maximum colors 1 5
Ecosystem
Cloud dependency No No
Software notes The machine is driven by Klipper firmware pre-installed on a proprietary 64-bit motherboard, ensuring rapid processing for advanced features like input shaping and pressure advance. The manufacturer provides a customized version of Cura (Elegoo Cura), but the printer is fully compatible with major third-party slicers such as PrusaSlicer and OrcaSlicer. Connectivity includes USB ports and a LAN network port, enabling remote management and direct print file transfers via the Fluidd or Mainsail web interfaces integrated into the system. The MK4S runs proprietary Prusa firmware based on Marlin, not GRBL. It is managed through PrusaSlicer (with over 180 official profiles included), Simplify3D, or Cura with community profiles. Files are loaded via USB, local network, or PrusaConnect and the Prusa mobile app; it is not compatible with LightBurn or LaserGRBL, being a filament printer. The machine can run fully offline with no cloud dependency, and receives regular firmware updates along with pre-tuned profiles for Prusament materials.

The differences that matter

  • Price: Neptune 4 Pro 299 € vs Original Prusa MK4S 3D Printer kit 819 € — Neptune 4 Pro wins (+174%)
  • Maximum colors: Neptune 4 Pro 1 vs Original Prusa MK4S 3D Printer kit 5 — Original Prusa MK4S 3D Printer kit wins (+400%)
  • Native Klipper: Neptune 4 Pro yes, Original Prusa MK4S 3D Printer kit no
  • Multicolor printing: Original Prusa MK4S 3D Printer kit yes, Neptune 4 Pro no
  • Requires external accessory: Original Prusa MK4S 3D Printer kit yes, Neptune 4 Pro no

Which one to choose

Choose Neptune 4 Pro if…

you value price, native klipper and maximum z height. «Klipper is an open-source firmware that offloads trajectory calculations from the microcontroller to a host computer, enabling all advanced features including input shaper and pressure advance. Native support eliminates the need to replace the firmware, a process that voids the warranty on some machines. Relevant for users who intend to tune advanced parameters; for basic use the difference from Marlin is minimal.»

See the Neptune 4 Pro sheet →

Choose Original Prusa MK4S 3D Printer kit if…

you value maximum colors, multicolor printing and max bed temperature. «The maximum number of colors indicates how many distinct color zones or materials can be used in one print without manual intervention. Two colors cover most practical uses, including soluble support. Higher values are useful for complex decorative models or color-coded prototypes. Each additional color increases print time due to transition purges, so the practical benefit should be weighed against the added time cost.»

See the Original Prusa MK4S 3D Printer kit sheet →

MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.