Kobra S1 Combo vs Original Prusa MK4S

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Kobra S1 Combo and Original Prusa MK4S are two fused filament fabrication (fff/fdm) in a similar class. Choose Kobra S1 Combo if closed chamber matters more; choose Original Prusa MK4S if price matters more.

Parameter
Anycubic Kobra S1 Combo Kobra S1 Combo Anycubic F2 · Intermediate
Identity
Launch year 2025 2025
Use tier F2 — Intermediate F2 — Intermediate
Price
Price (€) 749 € 999 €
Price updated on 06/2026
Universal specs
Dimensions (W×D×H) (cm) 48.4 × 48.4 × 59.3 cm 50 × 55 × 40 cm
Weight (kg) 18 kg
Work area (mm) 250 × 250 mm 250 × 210 mm
Z-axis height (mm) 250 mm 220 mm
Voltage (V) 230 V
Maximum speed 600 mm/s 500 mm/s
Declared precision 0.05 mm
Category specs
XY print surface (mm) 250 mm
Maximum Z height (mm) 250 mm
Kinematics corexy cartesian
Max nozzle temperature (°C) 320 °C
Max bed temperature (°C) 120 °C
Max print speed (mm/s) 600 mm/s
Closed chamber True False
Filament sensor True
Auto leveling mesh
Standard nozzle diameter (mm) 0.4 mm
Multi-extruder False False
Native Klipper False False
Input shaper True
Multicolor printing True True
Requires external accessory False True
Ecosystem
Cloud dependency No No
Software notes The printer works with Anycubic Slicer Next, derived from OrcaSlicer and optimized for the Anycubic ecosystem; it supports multi-plate management and object skipping during printing. Remote control and real-time monitoring are available through the Anycubic app (iOS and Android), connecting via LAN or cloud. The proprietary firmware is not currently open source; native Klipper compatibility is not supported. PrusaSlicer (optimized) and Prusa Connect for remote control. The machine accepts G-code from any slicer (Cura, Simplify3D) and communicates via USB, Ethernet or Wi-Fi using an open Marlin-based protocol. Compatible with OctoPrint and offline management. Does not require a Prusa account to print, unlike machines with proprietary firmware that block features without connection.

The differences that matter

  • Closed chamber: Kobra S1 Combo yes, Original Prusa MK4S no
  • Price: Kobra S1 Combo 749 € vs Original Prusa MK4S 999 € — Kobra S1 Combo wins (+33%)
  • Requires external accessory: Original Prusa MK4S yes, Kobra S1 Combo no
  • Work area: Kobra S1 Combo 250×250 mm vs Original Prusa MK4S 250×210 mm — Kobra S1 Combo wins (+19%)

Which one to choose

Choose Kobra S1 Combo if…

you value closed chamber, price and work area.

See the Kobra S1 Combo sheet →

Choose Original Prusa MK4S if…

it shows no measurable advantage over Kobra S1 Combo on the available specs: consider it on price or availability.

See the Original Prusa MK4S sheet →

MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.