Anycubic Kobra S1 Combo vs Prusa Research MK4S
Technical comparison · Fused filament fabrication (FFF/FDM)
Kobra S1 Combo leads on the available specs (starting with enclosed chamber); MK4S makes sense only for non-technical reasons (availability, support, ecosystem), or if the missing data matters in your case. On the category's overall technical index, Kobra S1 Combo scores 56/100 against 17/100 for MK4S.
| Parameter |
Kobra S1 Combo
Anycubic
F2 · Intermediate
|
MK4S
Prusa Research
F2 · Intermediate
|
|---|---|---|
| Identity | ||
| Launch year | 2025 | 2025 |
| Use tier | F2 — Intermediate | F2 — Intermediate |
| Price | ||
| Price (€) | 749 € | 999 € |
| Price updated on | 06/2026 | — |
| Universal specs | ||
| Dimensions (W×D×H) (cm) | 48.4 × 48.4 × 59.3 cm | 50 × 55 × 40 cm |
| Weight (kg) | 18 kg | — |
| Work area (mm) | 250 × 250 mm | 250 × 210 mm |
| Z-axis height (mm) | 250 mm | 220 mm |
| Voltage (V) | — | 230 V |
| Maximum speed | 600 mm/s | 500 mm/s |
| Declared precision | 0.05 mm | — |
| Category specs | ||
| Footprint X×Y (short side) (mm) | 250 mm | — |
| Build height Z (mm) | 250 mm | — |
| Kinematics | CoreXY | Cartesian |
| Max nozzle temperature (°C) | 320 °C | — |
| Max bed temperature (°C) | 120 °C | — |
| Max print speed (mm/s) | 600 mm/s | — |
| Enclosed chamber | True | False |
| Filament sensor | True | — |
| Auto bed leveling | Mesh | — |
| Standard nozzle diameter (mm) | 0.4 mm | — |
| Multi-extruder | False | False |
| Native Klipper | False | False |
| Input shaper | True | — |
| Multicolor printing | True | True |
| Multicolor requires accessory | False | True |
| Ecosystem | ||
| Cloud dependency | No | No |
| Software notes | The printer works with Anycubic Slicer Next, derived from OrcaSlicer and optimized for the Anycubic ecosystem; it supports multi-plate management and object skipping during printing. Remote control and real-time monitoring are available through the Anycubic app (iOS and Android), connecting via LAN or cloud. The proprietary firmware is not currently open source; native Klipper compatibility is not supported. | PrusaSlicer (optimized) and Prusa Connect for remote control. The machine accepts G-code from any slicer (Cura, Simplify3D) and communicates via USB, Ethernet or Wi-Fi using an open Marlin-based protocol. Compatible with OctoPrint and offline management. Does not require a Prusa account to print, unlike machines with proprietary firmware that block features without connection. |
The differences that matter
- Enclosed chamber: Kobra S1 Combo yes, MK4S no
- Price: Kobra S1 Combo 749 € vs MK4S 999 € — Kobra S1 Combo wins (+33%)
- Multicolor requires accessory: MK4S yes, Kobra S1 Combo no
- Work area: Kobra S1 Combo 250×250 mm vs MK4S 250×210 mm — Kobra S1 Combo wins (+19%)
Which one to choose
Choose Kobra S1 Combo if…
you value enclosed chamber, price and work area.
MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.