Anycubic Kobra S1 Combo vs Prusa Research MK4S 3D Printer kit

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Kobra S1 Combo leads on the available specs (starting with enclosed chamber); MK4S 3D Printer kit makes sense only for non-technical reasons (availability, support, ecosystem), or if the missing data matters in your case. On the category's overall technical index, Kobra S1 Combo scores 56/100 against 34/100 for MK4S 3D Printer kit.

Parameter
Anycubic Kobra S1 Combo Kobra S1 Combo Anycubic F2 · Intermediate
Identity
Launch year 2025 2025
Use tier F2 — Intermediate F2 — Intermediate
Price
Price (€) 749 € 819 €
Price updated on 06/2026
Universal specs
Dimensions (W×D×H) (cm) 48.4 × 48.4 × 59.3 cm 50 × 55 × 40 cm
Weight (kg) 18 kg 7 kg
Work area (mm) 250 × 250 mm 250 × 210 mm
Z-axis height (mm) 250 mm 220 mm
Power (W) 240 W
Voltage (V) 230 V
Maximum speed 600 mm/s 500 mm/s
Declared precision 0.05 mm
Category specs
Footprint X×Y (short side) (mm) 250 mm 250 mm
Build height Z (mm) 250 mm 220 mm
Kinematics CoreXY Cartesian
Max nozzle temperature (°C) 320 °C 290 °C
Max bed temperature (°C) 120 °C 120 °C
Max print speed (mm/s) 600 mm/s 500 mm/s
Enclosed chamber True False
Filament sensor True True
Auto bed leveling Mesh Mesh
Standard nozzle diameter (mm) 0.4 mm 0.4 mm
Multi-extruder False False
Native Klipper False False
Input shaper True True
Multicolor printing True True
Multicolor requires accessory False True
Max colors 5
Ecosystem
Cloud dependency No No
Software notes The printer works with Anycubic Slicer Next, derived from OrcaSlicer and optimized for the Anycubic ecosystem; it supports multi-plate management and object skipping during printing. Remote control and real-time monitoring are available through the Anycubic app (iOS and Android), connecting via LAN or cloud. The proprietary firmware is not currently open source; native Klipper compatibility is not supported. The MK4S runs proprietary Prusa firmware based on Marlin, not GRBL. It is managed through PrusaSlicer (with over 180 official profiles included), Simplify3D, or Cura with community profiles. Files are loaded via USB, local network, or PrusaConnect and the Prusa mobile app; it is not compatible with LightBurn or LaserGRBL, being a filament printer. The machine can run fully offline with no cloud dependency, and receives regular firmware updates along with pre-tuned profiles for Prusament materials.

The differences that matter

  • Enclosed chamber: Kobra S1 Combo yes, MK4S 3D Printer kit no
  • Multicolor requires accessory: MK4S 3D Printer kit yes, Kobra S1 Combo no
  • Max print speed: Kobra S1 Combo 600 mm/s vs MK4S 3D Printer kit 500 mm/s — Kobra S1 Combo wins (+20%)
  • Work area: Kobra S1 Combo 250×250 mm vs MK4S 3D Printer kit 250×210 mm — Kobra S1 Combo wins (+19%)
  • Build height Z: Kobra S1 Combo 250 mm vs MK4S 3D Printer kit 220 mm — Kobra S1 Combo wins (+14%)

Which one to choose

Choose Kobra S1 Combo if…

you value enclosed chamber, max print speed and work area.

See the Kobra S1 Combo sheet →

MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.