Anycubic Kobra S1 ACE 2 Pro Combo vs Prusa Research MK4S

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Kobra S1 ACE 2 Pro Combo leads on the available specs (starting with price); MK4S makes sense only for non-technical reasons (availability, support, ecosystem), or if the missing data matters in your case. On the category's overall technical index, Kobra S1 ACE 2 Pro Combo scores 60/100 against 17/100 for MK4S.

Parameter
Prusa Research MK4S MK4S Prusa Research F2 · Intermediate
Identity
Launch year 2026 2025
Use tier F2 — Intermediate F2 — Intermediate
Price
Price (€) 599 € 999 €
Price updated on 06/2026
Universal specs
Dimensions (W×D×H) (cm) 40 × 41 × 49 cm 50 × 55 × 40 cm
Weight (kg) 21.7 kg
Work area (mm) 250 × 250 mm 250 × 210 mm
Z-axis height (mm) 250 mm 220 mm
Power (W) 1300 W
Voltage (V) 230 V
Maximum speed 600 mm/s 500 mm/s
Declared precision 0.1 mm
Category specs
Footprint X×Y (short side) (mm) 250 mm
Build height Z (mm) 250 mm
Kinematics CoreXY Cartesian
Max nozzle temperature (°C) 320 °C
Max bed temperature (°C) 120 °C
Max print speed (mm/s) 600 mm/s
Enclosed chamber True False
Filament sensor True
Auto bed leveling Mesh
Standard nozzle diameter (mm) 0.4 mm
Multi-extruder False False
Native Klipper True False
Input shaper True
Multicolor printing true True
Multicolor requires accessory false True
Max colors 8
Ecosystem
Cloud dependency No No
Software notes Compatible with the main slicers on the market. It supports cloud connectivity via the Anycubic app and Wi-Fi for remote monitoring, while still allowing offline use via USB. PrusaSlicer (optimized) and Prusa Connect for remote control. The machine accepts G-code from any slicer (Cura, Simplify3D) and communicates via USB, Ethernet or Wi-Fi using an open Marlin-based protocol. Compatible with OctoPrint and offline management. Does not require a Prusa account to print, unlike machines with proprietary firmware that block features without connection.

The differences that matter

  • Price: Kobra S1 ACE 2 Pro Combo 599 € vs MK4S 999 € — Kobra S1 ACE 2 Pro Combo wins (+67%)
  • Enclosed chamber: Kobra S1 ACE 2 Pro Combo yes, MK4S no
  • Native Klipper: Kobra S1 ACE 2 Pro Combo yes, MK4S no
  • Multicolor requires accessory: MK4S yes, Kobra S1 ACE 2 Pro Combo no
  • Work area: Kobra S1 ACE 2 Pro Combo 250×250 mm vs MK4S 250×210 mm — Kobra S1 ACE 2 Pro Combo wins (+19%)

Which one to choose

Choose Kobra S1 ACE 2 Pro Combo if…

you value price, enclosed chamber and native klipper.

See the Kobra S1 ACE 2 Pro Combo sheet →

MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.