Anycubic Kobra S1 Combo vs Elegoo Neptune 4 Pro

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Kobra S1 Combo and Neptune 4 Pro are two fused filament fabrication (fff/fdm) in a similar class. Choose Kobra S1 Combo if enclosed chamber matters more; choose Neptune 4 Pro if price matters more. On the category's overall technical index, Kobra S1 Combo scores 56/100 against 38/100 for Neptune 4 Pro.

Parameter
Anycubic Kobra S1 Combo Kobra S1 Combo Anycubic F2 · Intermediate
Elegoo Neptune 4 Pro Neptune 4 Pro Elegoo F2 · Intermediate
Identity
Launch year 2025 2023
Use tier F2 — Intermediate F2 — Intermediate
Price
Price (€) 749 € 299 €
Price updated on 06/2026
Universal specs
Dimensions (W×D×H) (cm) 48.4 × 48.4 × 59.3 cm 47.5 × 44.5 × 51.5 cm
Weight (kg) 18 kg 8.9 kg
Work area (mm) 250 × 250 mm 225 × 225 mm
Z-axis height (mm) 250 mm 265 mm
Maximum speed 600 mm/s 500 mm/s
Declared precision 0.05 mm 0.1 mm
Category specs
Footprint X×Y (short side) (mm) 250 mm 225 mm
Build height Z (mm) 250 mm 265 mm
Kinematics CoreXY Cartesian
Max nozzle temperature (°C) 320 °C 300 °C
Max bed temperature (°C) 120 °C 110 °C
Max print speed (mm/s) 600 mm/s 500 mm/s
Enclosed chamber True False
Filament sensor True True
Auto bed leveling Mesh Mesh
Standard nozzle diameter (mm) 0.4 mm 0.4 mm
Multi-extruder False False
Native Klipper False True
Input shaper True True
Multicolor printing True False
Multicolor requires accessory False False
Max colors 1
Ecosystem
Cloud dependency No No
Software notes The printer works with Anycubic Slicer Next, derived from OrcaSlicer and optimized for the Anycubic ecosystem; it supports multi-plate management and object skipping during printing. Remote control and real-time monitoring are available through the Anycubic app (iOS and Android), connecting via LAN or cloud. The proprietary firmware is not currently open source; native Klipper compatibility is not supported. The machine is driven by Klipper firmware pre-installed on a proprietary 64-bit motherboard, ensuring rapid processing for advanced features like input shaping and pressure advance. The manufacturer provides a customized version of Cura (Elegoo Cura), but the printer is fully compatible with major third-party slicers such as PrusaSlicer and OrcaSlicer. Connectivity includes USB ports and a LAN network port, enabling remote management and direct print file transfers via the Fluidd or Mainsail web interfaces integrated into the system.

The differences that matter

  • Price: Kobra S1 Combo 749 € vs Neptune 4 Pro 299 € — Neptune 4 Pro wins (+151%)
  • Enclosed chamber: Kobra S1 Combo yes, Neptune 4 Pro no
  • Native Klipper: Neptune 4 Pro yes, Kobra S1 Combo no
  • Multicolor printing: Kobra S1 Combo yes, Neptune 4 Pro no
  • Work area: Kobra S1 Combo 250×250 mm vs Neptune 4 Pro 225×225 mm — Kobra S1 Combo wins (+23%)

Which one to choose

Choose Kobra S1 Combo if…

you value enclosed chamber, multicolor printing and work area.

See the Kobra S1 Combo sheet →

Choose Neptune 4 Pro if…

you value price, native klipper and build height z.

See the Neptune 4 Pro sheet →

MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.