Anycubic Kobra S1 Combo vs Elegoo Neptune 4 Plus

Technical comparison · Fused filament fabrication (FFF/FDM)

In brief

Kobra S1 Combo and Neptune 4 Plus are two fused filament fabrication (fff/fdm) in a similar class. Choose Kobra S1 Combo if enclosed chamber matters more; choose Neptune 4 Plus if price matters more. On the category's overall technical index, Kobra S1 Combo scores 56/100 against 42/100 for Neptune 4 Plus.

Parameter
Anycubic Kobra S1 Combo Kobra S1 Combo Anycubic F2 · Intermediate
Elegoo Neptune 4 Plus Neptune 4 Plus Elegoo F2 · Intermediate
Identity
Launch year 2025 2023
Use tier F2 — Intermediate F2 — Intermediate
Price
Price (€) 749 € ~300–400 €
Price updated on 06/2026
Universal specs
Dimensions (W×D×H) (cm) 48.4 × 48.4 × 59.3 cm 53.3 × 51.7 × 63.8 cm
Weight (kg) 18 kg 14.4 kg
Work area (mm) 250 × 250 mm 320 × 320 mm
Z-axis height (mm) 250 mm 385 mm
Maximum speed 600 mm/s 500 mm/s
Declared precision 0.05 mm 0.1 mm
Category specs
Footprint X×Y (short side) (mm) 250 mm 320 mm
Build height Z (mm) 250 mm 385 mm
Kinematics CoreXY Cartesian
Max nozzle temperature (°C) 320 °C 300 °C
Max bed temperature (°C) 120 °C 110 °C
Max print speed (mm/s) 600 mm/s 500 mm/s
Enclosed chamber True False
Filament sensor True True
Auto bed leveling Mesh Mesh
Standard nozzle diameter (mm) 0.4 mm 0.4 mm
Multi-extruder False False
Native Klipper False True
Input shaper True True
Multicolor printing True False
Multicolor requires accessory False False
Max colors 1
Ecosystem
Cloud dependency No No
Software notes The printer works with Anycubic Slicer Next, derived from OrcaSlicer and optimized for the Anycubic ecosystem; it supports multi-plate management and object skipping during printing. Remote control and real-time monitoring are available through the Anycubic app (iOS and Android), connecting via LAN or cloud. The proprietary firmware is not currently open source; native Klipper compatibility is not supported. The printer operates with Klipper firmware pre-installed on a 64-bit ARM processor, enabling advanced standard features like input shaping and pressure advance. The user interface is managed via a removable capacitive touchscreen and a dedicated web interface (Fluidd or Mainsail) for remote control and monitoring via Wi-Fi or LAN connection. For file preparation, the machine is compatible with major slicers on the market, including Elegoo Cura (bundled by the manufacturer), UltiMaker Cura, PrusaSlicer, and OrcaSlicer.

The differences that matter

  • Price: Kobra S1 Combo 749 € vs Neptune 4 Plus 350 € — Neptune 4 Plus wins (+114%)
  • Work area: Kobra S1 Combo 250×250 mm vs Neptune 4 Plus 320×320 mm — Neptune 4 Plus wins (+64%)
  • Build height Z: Kobra S1 Combo 250 mm vs Neptune 4 Plus 385 mm — Neptune 4 Plus wins (+54%)
  • Enclosed chamber: Kobra S1 Combo yes, Neptune 4 Plus no
  • Native Klipper: Neptune 4 Plus yes, Kobra S1 Combo no

Which one to choose

Choose Kobra S1 Combo if…

you value enclosed chamber, multicolor printing and max print speed.

See the Kobra S1 Combo sheet →

Choose Neptune 4 Plus if…

you value price, work area and build height z.

See the Neptune 4 Plus sheet →

MakerSpecs is an independent atlas. We don't sell products: this comparison links to both sheets, where you'll find complete data and official links.